[Translate to english:] Qualitätskontrollen und Gehaltsbestimmungen in Nahrungsergänzungsmitteln

Dietary Supplements

Analytical procedures for quality testing and content determination

Dietary supplements are foodstuffs to improve the supply of the human metabolism with particular nutrients or active substances such as vitaminsminerals, secondary phytochemicals (plant metabolites), trace elements, etc.  

In Switzerland, distinctions are made between two categories. Enriched foodstuffs and low- dose vitamin preparations come under the foodstuff legislation as dietary or food supplements. High-dose vitamin preparations and claims of their medicinal effects are regulated in the legislation on medicinal products.

If you require a determination of the content of nutrients and active ingredients in accordance with the Foodstuffs Act, we can carry these analyses out for you in our ISO / IEC 17025- accredited Swiss foodstuffs laboratory. We test for all common vitamins according to current methods. Quick, competent and reliable.

If your dietary supplements fall under the Law on Medicinal Products, then your analyses can be carried out under GMP conditions in our Swissmedic accredited and FDA certified area for pharmaceutical analysis. We would be pleased to carry out the analysis for you in accordance with your permitted methods or we can provide support in method development and validation.


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Sascha Theobald

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Dietary supplements are products that contain vitaminsminerals secondary phytochemicals or other substances with a specific nutritional or physiological effect in a concentrated form, and in which these substances are used to complement the diet. Frequently used application forms are capsules, tablets, liquids or powder.

Various forms of application for dietary supplements
Various forms of application for dietary supplements

Legal requirements

According to the Swiss Food Law, dietary supplements are judged to be Special Foodstuffs which contribute to the achievement of particular nutritional physiological effects (Article 2 Section 1, 22 of the Ordinance of the Swiss Federal Department of Home Affairs over Special Foodstuffs). Dietary supplements that fulfil the special and general requirements embedded in this Ordinance are marketable without need for approval. In contrast to the EU, Switzerland has a positive list of permitted health claims. New types of dietary supplements or dietary supplements with new health claims do however require approval.

It is frequently difficult to differentiate between dietary supplements and medicines. This is performed by looking at the intended purpose: firstly via the product composition (object purpose), and secondly at its presentation and promotion from the point of view of the manufacturer (subjective purpose). A classification of plant extracts for the differentiation of medicines from foodstuffs arises from the “List for the Categorisation of Plant Substances” (“Liste zur Einstufung pflanzlicher Stoffe”) of the Swiss Federal Office for Public Health (BAG) which was published in collaboration with Swissmedic to ensure health-related harmlessness with corresponding explanations.

In Switzerland the following legal guidelines must be observed for dietary supplements:

  • The Swiss Federal Law on Foodstuffs and Consumer Products (LMG) from 9th October 1992 (updated 1st October 2013)
  • Ordinance on Foodstuffs and Consumer Products (LGV) from 23rd November 2005 (updated 1st January 2013)
  • Ordinance of the Swiss Federal Department of Home Affairs on the Labelling and Advertising of Foodstuffs (LKV) from 23rd November 2005 (updated 1st January 2013)
  • Ordinance of the Swiss Federal Department of Home Affairs on Special Foodstuffs from 23rd November 2005 (updated 1st January 2012)

European legislation in relation to dietary supplements:

  • Regulation (EC) No. 1924/2006 of the European Parliament and of the Council from the 20th December 2006 on the nutritional and health claims of foodstuffs (Health Claims)
  • Regulation (EC) No. 258/97 of the European Parliament and of the Council from 20th January 1997 on novel foods and novel food ingredients (Novel Food Regulation)

In addition, recommended dosages, maximum and minimum values of possible ingredients and regulations for labelling and packaging design must be observed.



Typical ingredients in dietary supplements in Switzerland could be divided into the following substance classes. The use of these substances is dependent on the purpose of the preparation (e.g. for dietary and weight reduction purposes, or in the case of cardiovascular complaints):

  • Minerals and vitamins: There are legal maximum and minimum values for these.
  • Antioxidants
  • Secondary phytochemicals (e.g. anthocyanins, carotenoids, phytosterines, saponins, polyphenols, flavonoids etc.)
  • Coenzyme Q10
  • Creatine
  • L-Carnitine
  • Phytoestrogens

UFAG LABORATORIEN can offer an extensive range of analyses on many of these substance classes. In some cases, these are performed in collaboration with specialised partner laboratories. Examples of this are:

  • Vitamins
  • Minerals
  • Anthocyanins:
    • a) Total anthocyanins 
    • b) Qualitative analysis 
    • c) Quantitative analysis of anthocyanins present 
    • d) Identification and quantification of all detectable anthocyanins
  • Ginsenosides in products with ginseng roots
  • Catechins in products with green tea extract, with expulsion of the levels of catechin, epicatechin, epicatechin-3-gallate and epigallocatechin gallate (EGCG)
  • Aloin in products with aloe vera: Due to the positive image of aloe vera and its relatively high commodity prices, it is frequently falsified. By analogy with other medicinal plants, a sound quality control is therefore recommended.
  • L-carnitine: free and bonded
  • Coenzyme Q10 (Ubichinon)
  • Carotenoids such as beta-carotene, canthaxanthin, lutein, zeaxanthin or astaxanthin
  • Phytoestrogens: Isoflavones as a multi-method with expulsion of daidzin, glycitin, genistin, daidzein, glycitein, genistein, coumestrol and total isoflavones
  • Oligomere proanthocyanidins (OPC)
  • ORAC test for antioxidants: An ORAC test is used to determine what is known as the antioxidant capacity of a food, such as fruit juice or food supplements for example.
  • Polyphenols: photometric determination of total polyphenols using the Folin-Ciocalteu reagent
  • Pomegranate components such as punicalagin and ellagic acid
Sample preparation: The ingredients of a dietary supplement are determined
Sample preparation: The ingredients of a dietary supplement are determined

Our services in detail:

HPLC analyses are used frequently for the investigation of dietary supplements
HPLC analyses are used frequently for the investigation of dietary supplements

Infrastructure and Methods

All instrumental resources at a glance. Large selection of instruments and technology from UFAG Laboratories


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Do you have any questions regarding the testing of your products?

We will be happy to advise you!