Publications

Bioanalysis and classical analysis

The biotechnology trend in the pharmaceutical industry remains unbroken. In 2011, around eight times more biotechnically produced drugs were dispensed than just ten years previously. These drugs help with the successful treatment of some severe or even life-threatening diseases.

In contrast with classical chemical-pharmaceutical substances, biological substances are mainly complex, high-molecular structures such as proteins or oligonucleotides. Correspondingly, the analytical methods for the identification, quantification and characterisation of biomolecules are significantly different from classical analysis dealing with comparatively small organic compounds.

UFAG LABORATORIEN has established bioanalytical methods for proteins. The portfolio includes electrophoretic methods such as SDS-PAGE, IEF and 2D combinations thereof, blotting techniques as well as determination of the amino acid composition.

In his article “Biotechnology in the pharma industry - Differences between classical analysis and bioanalysis”, published in the German journal Chemie Plus 03/2013, Martin Knauf provides an overview of the most important bioanalytical methods and their differences compared with the classical analysis of small molecules.

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